Severe Selenium Deficiency Secondary to Chylous Loss
Eva de Berranger MD
Division of Gastroenterology, Hepatology and Nutrition
Search for more papers by this authorStéphanie Colinet MD
Division of Gastroenterology, Hepatology and Nutrition
Search for more papers by this authorCorresponding Author
Laurent Michaud MD
Division of Gastroenterology, Hepatology and Nutrition
Correspondence: L. Michaud, Unité de Gastro-entérologie, Hépatologie et Nutrition, Clinique de Pédiatrie, Hôpital Jeanne de Flandre, 59037 Lille cedex, France. Electronic mail may be sent to [email protected].Search for more papers by this authorGeorge Marie Brévière MD
Division of Cardiology, Department of Pediatrics University Children's Hospital and Faculty of Medicine, Lille, France
Search for more papers by this authorDominique Turck MD, PhD
Division of Gastroenterology, Hepatology and Nutrition
Search for more papers by this authorFrédéric Gottrand MD, PhD
Division of Gastroenterology, Hepatology and Nutrition
Search for more papers by this authorEva de Berranger MD
Division of Gastroenterology, Hepatology and Nutrition
Search for more papers by this authorStéphanie Colinet MD
Division of Gastroenterology, Hepatology and Nutrition
Search for more papers by this authorCorresponding Author
Laurent Michaud MD
Division of Gastroenterology, Hepatology and Nutrition
Correspondence: L. Michaud, Unité de Gastro-entérologie, Hépatologie et Nutrition, Clinique de Pédiatrie, Hôpital Jeanne de Flandre, 59037 Lille cedex, France. Electronic mail may be sent to [email protected].Search for more papers by this authorGeorge Marie Brévière MD
Division of Cardiology, Department of Pediatrics University Children's Hospital and Faculty of Medicine, Lille, France
Search for more papers by this authorDominique Turck MD, PhD
Division of Gastroenterology, Hepatology and Nutrition
Search for more papers by this authorFrédéric Gottrand MD, PhD
Division of Gastroenterology, Hepatology and Nutrition
Search for more papers by this authorAbstract
Selenium deficiency is observed in patients with poor intake. We report the first case of a child with lymphangiomatosis who presented a myopathy associated with severe cardiomyopathy secondary to selenium deficiency due to selenium loss in chylous fluid.
References
- 1Lombeck I, Kasperek K, Harbisch HD, et al. The selenium state of children. Eur J Pediatr. 1978; 128: 213–223.
- 2Rayman MP. The importance of selenium to human health. Lancet. 2000; 356: 233–241.
- 3Thomas AG, Miller V, Shenkin A, Fell GS, Taylor F. Selenium and glutathione peroxidase status in paediatric health and gastrointestinal disease. J Pediatr Gastroenterol Nutr. 1994; 19: 213–219.
- 4Greene HL, Hambidge KM, Scanler R, Tsang RC. Guidelines for the use of vitamins, trace elements, calcium, magnesium, and phosphorus in infants and children receiving total parenteral nutrition: report of the Subcommittee on Pediatric Parenteral Nutrient Requirements, from the Committee on Clinical Practices Issues of the American Society for Clinical Nutrition. Am J Clin Nutr. 1988; 48: 1324–1342.
- 5Litov RE, Combs GF. Selenium in pediatric nutrition. Pediatrics. 1991; 87: 339–351.
- 6Hatanaka N, Nakaden H, Yamamoto Y, Matsuo S, Fujikawa T, Matsusue S. Selenium kinetics and change in glutathione peroxidase activities in patients receiving long-term parenteral nutrition and effects of supplementation with selenite. Nutrition. 2000; 16: 22–26.
- 7Yusuf SW, Rehman Q, Casscells W. Cardiomyopathy in association with selenium deficiency: a case report. JPEN J Parenter Enteral Nutr. 2002; 26: 63–66.
- 8Kelly DA, Coe AW, Shenkin A, Lake BD, Walker-Smith JA. Symptomatic selenium deficiency in a child on home parenteral nutrition. J Pediatr Gastroenterol Nutr. 1988; 7: 783–786.
- 9Johnson RA, Baker SS, Fallon JT, et al. An occidental case of fatal cardiomyopathy and selenium deficiency. N Engl J Med. 1981; 304: 1201–1202.
- 10Collip PJ, Chen SY. Cardiomyopathy and selenium deficiency in a two year old girl. N Engl J Med. 1981; 304: 1304–1305.
- 11Chariot P, Bignani O. Skeletal muscle disorders associated with selenium deficiency in humans. Muscle Nerve. 2003; 27: 662–668.